Macular neurodegenerative and vascular changes on OCTA in sickle cell disease are not related to its ocular and systemic complications.

Rajani Priya BrandsenBart J BiemondGulsum Z NasimErfan NurReinier O SchlingemannRoselie M H Diederen

Published in: Retina (Philadelphia, Pa.) (2024)

Macular abnormalities were common, but did not result in visual impairment. No relation with SCR presence/severity was found. While OCTA-imaging is suitable for detecting maculopathy, it appears to have no diagnostic value in identifying patients at risk for SCR.

Keyphrases

sickle cell disease
optical coherence tomography
end stage renal disease
diabetic retinopathy
chronic kidney disease
ejection fraction
newly diagnosed
high resolution
prognostic factors
patient reported outcomes
risk factors
age related macular degeneration
cataract surgery
photodynamic therapy
optic nerve