Evaluation of diagnostic and prognostic candidate biomarkers in drug-induced liver injury versus other forms of acute liver damage.

Alejandro Cueto-SanchezHao NiuIsmael Álvarez-ÁlvarezBárbara López-LongarelaEnrique Del Campo-HerreraAida Ortega-AlonsoMiren Garcia-CortesJosé Pinazo-BanderaJudith Sanabria-CabreraJuan José Díaz-MochónMaría Isabel LucenaRaúl J AndradeCamilla StephensMercedes Robles-Diaz

Published in: British journal of clinical pharmacology (2023)

ccK18 appears promising in distinguishing DILI from autoimmune hepatitis, but less so from other forms of acute liver injury. Osteopontin demonstrates prognostic potential with higher levels detected in more severe cases regardless of aetiology.

Keyphrases

drug induced
liver injury
adverse drug
oxidative stress
emergency department
respiratory failure
early onset
intensive care unit
extracorporeal membrane oxygenation
human health