Purple Carrot Extract Exhibits A Neuroprotective Profile In The Nigrostriatal Pathway In The Reserpine-Induced Model Of Parkinson's Disease.

Ana Claudia Custódio-Silva Jose Ivo Araújo Beserra-Filho Beatriz Soares-SilvaAmanda Maria-MacêdoSuellen Silva-Martins Sara Pereira Silva José Ronaldo Santos Regina Helena Silva Daniel Araki Ribeiro Alessandra Mussi Ribeiro

Published in: Central nervous system agents in medicinal chemistry (2024)

CAR extract is effective to attenuate motor symptoms in rats associated with increased TH+ levels in the Ventral Tegmental Area (VTA) and SNpc, indicating the potential nutraceutical benefits of CAR extract in a progressive parkinsonism model induced by RES.

Keyphrases

oxidative stress
anti inflammatory
multiple sclerosis
diabetic rats
drug induced
spinal cord
high glucose
parkinson disease
deep brain stimulation
risk assessment
sleep quality
endothelial cells
physical activity
climate change