Spindle cell renal cell carcinoma diagnosed after sunitinib treatment for chromophobe renal cell carcinoma.

Ruriko Honda-TakinamiKei IshibashiAkifumi OnagiRyo TanjiKanako MatsuokaSeiji HoshiTomoyuki KoguchiJunya HataMichihiro YabeYuichi SatoHidenori AkaihataMasao KataokaSoichiro OgawaNobuhiro HagaYoshiyuki Kojima

Published in: IJU case reports (2020)

It appears that the primary tumor underwent epithelial-mesenchymal transition; further tissue specimen collection and analysis might be needed.

Keyphrases

renal cell carcinoma
epithelial mesenchymal transition
single cell
transforming growth factor
signaling pathway
stem cells
combination therapy
replacement therapy
mesenchymal stem cells