Time course of body composition changes in transgender adolescents during puberty suppression and sex hormone treatment.
Lidewij Sophia BoogersSterre Johanna Petronella ReijtenbaghChantal Maria WiepjesAdrianus Sarinus Paulus van TrotsenburgMartin den HeijerSabine Elisabeth HannemaPublished in: The Journal of clinical endocrinology and metabolism (2023)
Compared to peers, trans girls experienced ongoing lean mass decrease and fat mass increase during 3 years of PS while in trans boys smaller changes were observed that stabilized after one year. A large increase in lean mass Z-scores occurred only during the first year of testosterone treatment. In trans girls, body composition changed only slightly during GAHT. This information can improve counseling about treatment effects.