Proteogenomic Characterization Reveals Estrogen Signaling as a Target for Never-Smoker Lung Adenocarcinoma Patients without EGFR or ALK Alterations.

Seung-Jin Park Shinyeong Ju Sung-Ho Goh Byoung-Ha Yoon Jong-Lyul Park Jeong Hwan Kim Seonjeong Lee Sang-Jin Lee Yumi Kwon Wonyeop Lee Kyung Chan Park Geon Kook Lee Seog Yun Park Sunshin Kim Seon-Young Kim Ji-Youn Han Cheolju Lee

Published in: Cancer research (2024)

The proteogenomic landscape in never-smoker lung cancer without known driver mutations reveals prognostic proteins and enhanced estrogen signaling that can be targeted as a potential therapeutic strategy to improve patient outcomes.

Keyphrases

end stage renal disease
small cell lung cancer
ejection fraction
newly diagnosed
chronic kidney disease
estrogen receptor
peritoneal dialysis
prognostic factors
tyrosine kinase
single cell
cancer therapy
drug delivery
advanced non small cell lung cancer