Cryptolepine Analog Exhibits Antitumor Activity against Ehrlich Ascites Carcinoma Cells in Mice via Targeting Cell Growth, Oxidative Stress, and PTEN/Akt/mTOR Signaling Pathway.
Bishoy El-AaragEman S ShalaanAbdullah A S AhmedIbrahim El Tantawy El SayedWafaa M IbrahimPublished in: Anti-cancer agents in medicinal chemistry (2024)
Our findings showed the anticancer activity of CPE analog against EACs in mice mediated by regulation of the PTEN/Akt/mTOR signaling pathway.