Triple therapy temporary mechanical circulatory support as a bridge to triple-organ transplantation.
Omar M SharafAlex M ParkerMark S BleiweisEric I JengPublished in: Journal of cardiac surgery (2022)
Temporary mechanical circulatory support (MCS) systems are indicated to stabilize hemodynamically decompensating patients in cardiogenic shock refractory to medical management. These devices are currently used as short-term hemodynamic support to facilitate organ recovery or bridge to definitive therapy with durable MCS or heart transplantation. We present the sequential use of intra-aortic balloon pump, Impella 5.5®, and venoarterial extracorporeal membrane oxygenation as a bridge to heart-liver-kidney transplantation. The patient was supported for 78 days on Impella 5.5 and 95 days total temporary MCS. He had an uncomplicated postoperative course after triple-organ transplantation and was stable with no signs of rejection at 1-, 3-, 6-, and 12-month follow-up.
Keyphrases
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- kidney transplantation
- respiratory failure
- end stage renal disease
- ejection fraction
- newly diagnosed
- cell therapy
- heart failure
- chronic kidney disease
- peritoneal dialysis
- healthcare
- patients undergoing
- mechanical ventilation
- prognostic factors
- aortic valve
- squamous cell carcinoma
- intensive care unit
- locally advanced
- aortic dissection
- rectal cancer
- replacement therapy