Myricanol rescues dexamethasone-induced muscle dysfunction via a sirtuin 1-dependent mechanism.

Shengnan ShenQiwen LiaoJingxin LiuRuile PanSimon Ming-Yuen LeeLi-Gen Lin

Published in: Journal of cachexia, sarcopenia and muscle (2019)

Myricanol ameliorates dexamethasone-induced skeletal muscle wasting by activating SIRT1, which might be developed as a therapeutic agent for treatment of muscle atrophy and weakness.

Keyphrases

skeletal muscle
high glucose
diabetic rats
oxidative stress
low dose
high dose
insulin resistance
mouse model
drug induced
signaling pathway
endothelial cells
adipose tissue
smoking cessation
stress induced
myasthenia gravis