Cell Lines as Biological Models: Practical Steps for More Reliable Research.
Amanda Capes-DavisAmos BairochTanya BarrettEdward C BurnettWilhelm G DirksErin M HallLyn HealyDouglas A KnissChristopher KorchYuqin LiuRichard M NeveRaymond W NimsBarbara ParodiRebecca E SchweppeDouglas R StortsFang TianPublished in: Chemical research in toxicology (2019)
Research in toxicology relies on in vitro models such as cell lines. These living models are prone to change and may be described in publications with insufficient information or quality control testing. This article sets out recommendations to improve the reliability of cell-based research.