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Clinical significance of concomitant bacteriuria in patients with Staphylococcus aureus bacteraemia.

Matthaios Papadimitriou-OlivgerisDamien JacotLaurence SennBenoit Guery
Published in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2023)
This retrospective study, conducted at Lausanne University Hospital (2015-2021), compared Staphylococcus aureus bacteraemia (SABA) patients with or without concomitant bacteriuria (SABU). Among 448 included bacteraemic patients, 62 (13.8%) had S. aureus concurrently isolated from urine. In multivariate analysis, there was a significant difference in the odds of community-onset bacteraemia (P 0.030), malignancy (P 0.002), > 1 pair of positive blood cultures (P 0.037), and persistent bacteraemia for at least 48 h (P 0.045) in patients with concurrent SABU. No difference concerning mortality was found. On the other hand, SABU was associated with higher rates of SABA recurrence after antibiotic cessation.
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