Statins Are Associated With Increased Insulin Resistance and Secretion.
Fahim AbbasiCindy LamendolaChelsea S HarrisVander HarrisMing-Shian TsaiPragya TripathiFakhar AbbasGerald M ReavenPeter D ReavenMichael P SnyderSun H KimJoshua W KnowlesPublished in: Arteriosclerosis, thrombosis, and vascular biology (2021)
In individuals without type 2 diabetes, high-intensity atorvastatin for 10 weeks increases insulin resistance and insulin secretion. Over time, the risk of new-onset diabetes with statin use may increase in individuals who become more insulin resistant but are unable to maintain compensatory increases in insulin secretion.