Different relationships between epilepsy syndromes and autoimmune diseases.

João Chaves Bárbara LealAna SardoeiraVanessa CarvalhoRaquel SamõesJoel FreitasRui ChorãoAna Marta FerreiraSandra BrásJoão LopesJoão RamalheiraCarolina LemosPaulo Pinho CostaAntónio MarinhoBerta Martins da SilvaAntónio Martins da Silva

Published in: Epileptic disorders : international epilepsy journal with videotape (2023)

Our study indicates two relationship patterns: a bidirectional association between IGEs and autoimmune diseases and a unidirectional relationship between MTLE-HS and autoimmune diseases. The involvement of genetic susceptibility factors (such as the HLA system), autoinflammatory mechanisms, female sex, and antiseizure medications in these relationships are discussed.

Keyphrases

genome wide
dna methylation
copy number