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Comparison of Body Size, Morphomics, and Kidney Function as Covariates of High-Dose Methotrexate Clearance in Obese Adults with Primary Central Nervous System Lymphoma.

Manjunath Amit P PaiKenneth C DebackerBrian DerstineJune SullivanGrace L SuStewart C Wang
Published in: Pharmacotherapy (2020)
Common clinical variables coupled with vertebral body height are more predictive of first cycle MTX CL than BSA, alternate body size descriptors, and commonly used kidney function equations.
Keyphrases
  • high dose
  • low dose
  • metabolic syndrome
  • stem cell transplantation
  • type diabetes
  • body mass index
  • adipose tissue
  • weight loss
  • diffuse large b cell lymphoma
  • cerebrospinal fluid