Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma.
Teresa PaínoLorena González-MéndezLaura San-SegundoLuis-Antonio CorcheteSusana Hernández-GarcíaAndrea Díaz-TejedorEsperanza M AlgarínPedro MogollónMontserrat Martín-SánchezNorma C GutiérrezMaría-Victoria MateosMercedes GarayoaEnrique María OcioPublished in: Cancers (2020)
Altogether, our data support the clinical evaluation of the triple combination PIM-Pd for the treatment of patients with multiple myeloma.