Dose-dependent effects of oral cannabidiol and delta-9-tetrahydrocannabinol on serum anandamide and related N-acylethanolamines in healthy volunteers.

Timothy A CouttasCarola BoostFranziska Pahlisch Eliska B Sykorova Juliane K Mueller Beverly Jieu Judith E Leweke Inga Dammann Anna E HoffmannMartin LoefflerOliver Grimm Frank Enning Stephan F Miedl Andreas Meyer-Lindenberg Dagmar Koethe Cathrin Rohleder F Markus Leweke

Published in: BMJ mental health (2024)

-THC appears to enhance the CBD-induced response towards AEA and its congeners. Our results warrant further investigations into the potential of these lipid-derived mediators as metabolic measures for CBD dose prescription and co-cannabinoid administration.

Keyphrases

high glucose
diabetic rats
drug induced
endothelial cells
climate change