A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase.
Xuejie ChenYizhou LiuNatsuko FurukawaDa-Yun JinG Paul SavageDarrel W StaffordYoshitomo SuharaCraig M WilliamsJian-Ke TiePublished in: Journal of thrombosis and haemostasis : JTH (2021)
We discovered a vitamin K analogue that functions as a VKA and is tolerant to genetic variations in the target enzyme.