Echocardiographic findings in acromegaly: prevalence of concentric left ventricular remodeling in a large single-center cohort.
J M Hinojosa-AmayaE V VarlamovC G YedinakJ S CetasS McCartneyS BanskotaMaria FleseriuPublished in: Journal of endocrinological investigation (2021)
Early diagnosis of acromegaly and disease control should be attempted to prevent LVH/LV dysfunction and development of valvular heart disease. Concentric LV remodeling develops prior to obvious LV hypertrophy in almost a third of patients with acromegaly, which is a novel finding. Similar to other epidemiological studies, we found a high prevalence of LVH/LV dysfunction. Although possible, reversal of systolic and diastolic dysfunction is sporadic after treatment of acromegaly.
Keyphrases
- left ventricular
- oxidative stress
- heart failure
- growth hormone
- blood pressure
- hypertrophic cardiomyopathy
- acute myocardial infarction
- left atrial
- cardiac resynchronization therapy
- pulmonary hypertension
- mitral valve
- aortic stenosis
- risk factors
- atrial fibrillation
- ejection fraction
- amyotrophic lateral sclerosis
- early onset