Intersectionality of Socioecological Factors Associated With Cognitive Function Among Older Women With HIV in the United States: A Structural Equation Model Analysis Using Data From the Women's Interagency HIV Study.
Veronica P S Njie-CarrShijun ZhuKristen Alyce StaffordWeiqun TongMichael PlankeyAnjali SharmaJoel MilamMardge CohenMonica M DiazAnna A RubtsovaMargaret A FischlDeborah Konkle-ParkerDeborah GustafsonLeah H RubinPublished in: The Journal of the Association of Nurses in AIDS Care : JANAC (2022)
Increased life expectancy of people with HIV has health implications including the intersection of the long-term use of antiretroviral treatment, inflammatory events, and age-related immunosenescence. In a cross-sectional study utilizing using the Socio-Eecological Model, we identified pathways of cognitive function (CF) among 448 women with HIV, 50 years and older. A structural equation model showed the direct effects of mood (β = -0.25, p < .01), comorbidities (β = --0.13, p < .05), race (β = --0.13, p < .05), and abuse (β = 0.27, p < .001) on the latent variable CF. Substance and alcohol use, depressive symptoms, cigarette smoking, and the number of comorbidities are important considerations when designing interventions utilizing using a multi-level and intersectional lens to maximize positive CF outcomes.
Keyphrases
- hiv positive
- hiv infected
- antiretroviral therapy
- human immunodeficiency virus
- hiv aids
- hiv testing
- hepatitis c virus
- men who have sex with men
- cystic fibrosis
- depressive symptoms
- hiv infected patients
- physical activity
- south africa
- healthcare
- oxidative stress
- mental health
- sleep quality
- bipolar disorder
- metabolic syndrome
- polycystic ovary syndrome
- risk factors
- health information
- adipose tissue
- machine learning
- deep learning
- skeletal muscle
- insulin resistance
- weight loss
- replacement therapy