Impact of post-collection freezing delay on the reliability of serum metabolomics in samples reflecting the California mid-term pregnancy biobank.

Michael R La FranoSuzan L CarmichaelChen MaMacy HardleyTong ShenRon WongLorenzo RosalesKamil BorkowskiTheresa L PedersenGary M ShawDavid K StevensonOliver FiehnJohn W Newman

Published in: Metabolomics : Official journal of the Metabolomic Society (2018)

Despite extended post-collection freezing delays characteristic of some biobanks of opportunistically collected clinical samples, numerous metabolomic compounds had both stable levels and good concordance.

Keyphrases

mass spectrometry
preterm birth
pregnancy outcomes
pregnant women