Relay Adsorption in Metal-Organic Frameworks for One-Step Helium Purification at Ambient Temperature.

One-step He purification from natural gas represents a crucial solution for addressing the global He shortages. The prevailing method to produce high-grade He involves cryogenic distillation and ultralow temperature adsorption processes, which is highly cost- and energy-intensive. Separating and purifying He at ambient temperature is a great challenge because the fundamental limitation lies in the boiling point, polarizability, and kinetic diameters of CH 4 /N 2 /He gases. In this study, we seek to implement a relay adsorption strategy using Ni(ina) 2 and MIL-100(Cr) metal-organic frameworks (MOFs) to produce high-purity He from ternary mixtures (CH 4 , N 2 , and He) at ambient temperature. The CH 4 /He selectivity in Ni(ina) 2 and N 2 /He selectivity in MIL-100(Cr) both reach record 15.39 and 128.49, respectively, making the relay adsorption for helium purification highly efficient. The breakthrough experiments show that the two MOFs can sequentially adsorb CH 4 and N 2 in ternary mixtures, producing He with a purity of up to 99.99% in one step. The remarkable separation performance and stability of these MOFs underscore the industrial potential in purifying He at ambient temperature.