Non-invasive quantification of stem cell-derived islet graft size and composition.

Väinö Lithovius Salla Lahdenpohja Hazem Ibrahim Jonna Saarimäki-VireLotta UusitaloHossam Montaser Kirsi MikkolaCheng-Bin YimThomas KellerJohan Rajander Diego Balboa Tom BarsbyOlof SolinPirjo Nuutila Tove J Grönroos Timo Otonkoski

Published in: Diabetologia (2024)

F]FDOPA PET enable non-invasive assessment of SC-islet graft size and aspects of graft composition. These methods could be leveraged for optimising SC-islet cell replacement therapy in diabetes.

Keyphrases

replacement therapy
stem cells
type diabetes
smoking cessation
cardiovascular disease
cell therapy
single cell
computed tomography
glycemic control
adipose tissue
weight loss