Plasma tumour DNA as an early indicator of treatment response in metastatic castration-resistant prostate cancer.

Vincenza ConteducaDaniel WetterskogEmanuela ScarpiAlessandro RomanelGiorgia GurioliAnuradha JayaramCristian LolliDelila Gasi TandefeltGiuseppe SchepisiChiara CasadeiAnna WingateFederica MatteucciGiovanni PaganelliEnrique Gonzalez-BillalabeitiaFrancesca DemichelisUgo De GiorgiGerhardt Attard

Published in: British journal of cancer (2020)

We found that ptDNA assessment for therapy monitoring in mCRPC is feasible and provides data relevant to the clinical setting. Prospective evaluation of these findings is now merited.

Keyphrases

squamous cell carcinoma
small cell lung cancer
circulating tumor
electronic health record
single molecule
cell free
big data
machine learning
bone marrow
mesenchymal stem cells
nucleic acid
cell therapy
deep learning
data analysis
circulating tumor cells
replacement therapy
smoking cessation