Genital HSV-1 DNA detection is associated with a low inflammatory profile in HIV-uninfected South African women.
Andile MtshaliSinaye NgcapuFarzana OsmanNigel GarrettRavesh SinghAnne RompaloAdrian MindelLenine J P LiebenbergPublished in: Sexually transmitted infections (2020)
That HSV-1 DNA was more commonly detected and shed than HSV-2 emphasises the need for clinical screening of both viruses, not just HSV-2 in young women. Efforts to reduce genital inflammation may need to consider implementing additional strategies to mitigate a rise in HSV replication.