Depleted lamin B1: a possible marker of the involvement of senescence in endometriosis?

Helena MalvezziBruno Gallani VianaCristine DoboRenee Zon FilippiSérgio PodgaecCarla Azevedo Piccinato

Published in: Archives of gynecology and obstetrics (2018)

We observed reduced detection of lamin B1 in the ectopic endometrium raising the possibility that the presence of senescent cells might be contributing to the maintenance and progression of endometriosis by apoptosis resistance and peritoneal stress inherent of the disease.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
pi k akt
oxidative stress
stress induced
dna damage
endothelial cells
signaling pathway
loop mediated isothermal amplification
real time pcr