High serum 8-hydroxy-2'-deoxyguanosine levels predict DNA damage and aging in professional divers.

Ali Erdal Gunes Ozgur Yılmaz Celal Erbas Seyda Nur Dagli Hakim Celik

Published in: Revista da Associacao Medica Brasileira (1992) (2021)

It was found that air dives caused an increase in serum 8-hydroxy-2'-deoxyguanosine levels, leading to acute oxidative stress and aging. However, there is no chronic side effect, according to the study of samples taken from the control group. This was thought to be due to the relative sedentary life of the control group. The duration of the effect or the ability to return to normal values should be investigated with further studies planned with large populations.

Keyphrases

dna damage
oxidative stress
physical activity
liver failure
drug induced
mass spectrometry
dna repair
intensive care unit
respiratory failure
signaling pathway
induced apoptosis
hepatitis b virus
genetic diversity
extracorporeal membrane oxygenation
heat stress