Urinary 11-dehydrothromboxane B2 aspirin efficacy testing is sensitive to perioperative inflammation in pediatric solid-organ transplant patients.
Alexander A BoucherBrenton J FranciscoAmanda PfeifferMatthew MartinJanine MartinAmy ShovaJaimie D NathanGregory M TiaoLori Luchtman-JonesPublished in: Pediatric blood & cancer (2021)
Our data suggest that urine thromboxane production may be an underappreciated reflection of postoperative inflammation. Validation of pediatric normal ranges for UTxB2 is a critical next step.
Keyphrases
- oxidative stress
- end stage renal disease
- patients undergoing
- ejection fraction
- chronic kidney disease
- low dose
- prognostic factors
- cardiac surgery
- big data
- type diabetes
- cardiovascular events
- acute coronary syndrome
- acute kidney injury
- patient reported outcomes
- percutaneous coronary intervention
- coronary artery disease
- atrial fibrillation
- artificial intelligence
- data analysis