Effect of continuous local dexamethasone on tissue biomechanics and histology after inhalational burn in a preclinical model.

Ronit MalkaGabriela GonzalesWill DetarLisa M MarinelliChristine M LeeAlisa IsaacSolaleh MiarStacy CookTeja Guda Gregory R Dion

Published in: Laryngoscope investigative otolaryngology (2023)

Local dexamethasone delivery increases VF stiffness and degree of inflammation compared to uncoated ETTs in an acute laryngeal burn model, reflected in early biomechanical and histologic changes in an inhalational burn model.

Keyphrases

low dose
high dose
wound healing
oxidative stress
liver failure
intensive care unit
drug induced
cell therapy
hepatitis b virus