Comparison of Open-Access, Trough-Only Online Calculators Versus Trapezoidal Method for Calculation of Vancomycin Area Under the Curve (AUC).
Elizabeth KeilRebekah H WrennConnor R DeriCara N SlatonJenny ShrobaAlice ParishAlaattin ErkanliJustin SpiveyPublished in: The Annals of pharmacotherapy (2022)
The AUC calculator most closely aligned with TM was VancoPK, whereas other included calculators were statistically different. Owing to the cost and complexity of obtaining multiple levels, our findings support using a single steady-state trough using VancoPK as an alternative to TM for calculation of vancomycin AUC.