Disease survival and progression in TARDBP ALS patients from Sardinia, Italy.
Giuseppe BorgheroFrancesca PiliAntonella MuroniTommaso ErcoliMaria Ida PateriSilvy PilottoAlessandra MaccabeoGiovanni DefazioPublished in: Journal of neurology (2023)
TARDBP patients have a better survival/prognosis than C9orf72-positive and nmALS patients. King's staging also suggested that the higher survival rate and the slower progression associated with the TARDBP mutation could mainly be attributed to the longer time elapsed between King's stages 2B to 3.