Prediction of Early Symptom Remission in Two Independent Samples of First-Episode Psychosis Patients Using Machine Learning.
Rigas-Filippos SoldatosMicah CearnsMette Ø NielsenCostas KolliasLida-Alkisti XenakiPentagiotissa StefanatouIrene RalliStefanos DimitrakopoulosAlex HatzimanolisIoannis KosteletosIlias I VlachosMirjana SelakovicStefania FoteliNikolaos NianiakasLeonidas MantonakisTheoni F TriantafyllouAggeliki NtigridakiVanessa ErmiliouMarina VoulgarakiEvaggelia PsarraMikkel E SørensenKirsten B BojesenKaren TangmoseAnne M SigvardKaren S AmbrosenToni MerittWarda SyedaBirte Y GlenthøjNikolaos KoutsoulerisChristos PantelisBjørn H EbdrupNikos StefanisPublished in: Schizophrenia bulletin (2021)
Using items from common and validated clinical scales, our model significantly predicted early remission in patients with first-episode psychosis. Although replicated in an independent cohort, forward testing between machine learning models and clinicians' assessment should be undertaken to evaluate the possible utility as a routine clinical tool.