Clinical development success rates and social value of pediatric Phase 1 trials in oncology.

Mateusz T WasylewskiKarolina StrzebonskaMagdalena KopernyMaciej PolakJonathan KimmelmanMarcin Waligora

Published in: PloS one (2020)

Our analysis shows that treatments tested in pediatric Phase 1 trials in oncology have low rates of regulatory approval. However, a large proportion of Phase 1 trials inform further testing and development of tested interventions.

Keyphrases

healthcare
mental health
physical activity
young adults
childhood cancer