miRNA omics reveal neferine induces apoptosis through Ca 2+ mediated endoplasmic reticulum stress pathway in human endometrial cancer.

Fei-Fei MaRun-Hui MaKiran ThakurJian-Guo ZhangHui CaoZhao-Jun WeiJesus Simal-Gandara

Published in: Phytomedicine : international journal of phytotherapy and phytopharmacology (2024)

-mediated ERS pathway and the PI3K/AKT pathway, thereby inducing apoptosis in EC cells, confirming the potential role of Nef in the prevention and treatment of EC.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
endometrial cancer
cell cycle arrest
endothelial cells
oxidative stress
single cell
signaling pathway
cell death
gene expression
induced pluripotent stem cells
combination therapy
pi k akt
human health
replacement therapy