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Measuring reliable change in cognition using the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).

Christopher J CrockfordJudith NewtonKatie LonerganCaoifa MaddenIain MaysMeabhdh O'SullivanEmmet CostelloMarta Pinto-GrauAlice VajdaMark HeverinNiall PenderAmmar Al ChalabiOrla HardimanSharon Abrahams
Published in: Amyotrophic lateral sclerosis & frontotemporal degeneration (2017)
The alternate forms of the ECAS possess excellent test-retest reliability in a healthy control sample, with no significant practice effects. The use of conservative RCI scores is recommended. Therefore, a change of ≥8, ≥4, and ≥9 for ALS Specific, ALS Non-Specific, and ECAS Total score is required for reliable change.
Keyphrases
  • amyotrophic lateral sclerosis
  • healthcare
  • primary care
  • high throughput
  • mild cognitive impairment
  • multiple sclerosis
  • single cell