Tau-induced deficits in nonsense-mediated mRNA decay contribute to neurodegeneration.
Gabrielle ZunigaSimon LevyPaulino RamirezJasmine De MangeElias GonzalezMaria GamezBess FrostPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)
Our studies suggest that NMD activators should be explored for their potential therapeutic value to patients with tauopathies.