Clofarabine monotherapy in two patients with refractory Langerhans cell histiocytosis.
Masahiro IrieTomohiro NakanoSaori KatayamaTasuku SuzukiKunihiko MoriyaYuko WatanabeNobu SuzukiYuka Saitoh-NanjyoMasaei OnumaTakeshi RikiishiHidetaka NiizumaYoji SasaharaShigeo KurePublished in: Cancer reports (Hoboken, N.J.) (2021)
Although large-scale studies are warranted, CLO monotherapy could be a therapeutic option for high efficacy and feasibility besides other intensive combination chemotherapies or allogeneic hematopoietic stem cell transplantation for refractory LCH without risk organ involvement in children.