Iron homeostasis is altered in response to hypoxia and hypothermic preconditioning in brain glial cells

Latife Arzu Aral Mehmet Ali Ergün Ayşe Başak Engin Alp Ozgun Borcek Hayrunnisa Bolay Belen

Published in: Turkish journal of medical sciences (2020)

The data suggest that hypothermic preconditioning affects cellular iron homeostasis by regulating the storage and transfer proteins of iron. Regulation of the cellular iron traffic may prevent glial cells from experiencing the detrimental effects of hypoxia-related inflammation.

Keyphrases

iron deficiency
ischemia reperfusion injury
oxidative stress
cerebral ischemia
neuropathic pain
air pollution
white matter
resting state
signaling pathway
cell proliferation
subarachnoid hemorrhage
artificial intelligence
drug induced