Combined aortic valve and coronary artery calcifications in lung cancer screening as predictors of death from cardiovascular disease.
Yeqing ZhuRowena YipJoseph ShemeshArtit C JirapatnakulDavid F YankelevitzClaudia I HenschkePublished in: European radiology (2020)
• Aortic valve calcification (AVC) and coronary artery calcification (CAC) are both due to atherosclerotic disease. The prevalence of AVC in lung cancer screening cohort significantly increased with the increasing severity of CAC. • CAC and AVC were significant predictors of cardiovascular disease (CVD) death when considered alone. Participants who underwent lung cancer screening with AVC > 0 and CAC ≥ 4 had more than a 2-fold increased risk of CVD death than the group with AVC = 0 and CAC < 4, when adjusted for other risk factors.
Keyphrases
- aortic valve
- coronary artery
- cardiovascular disease
- transcatheter aortic valve replacement
- risk factors
- transcatheter aortic valve implantation
- aortic valve replacement
- aortic stenosis
- pulmonary artery
- chronic kidney disease
- type diabetes
- heart failure
- cardiovascular events
- coronary artery disease
- metabolic syndrome
- cardiovascular risk factors
- left ventricular
- pulmonary arterial hypertension