Model-based analysis of treatment effects of paclitaxel microspheres in a microscopic peritoneal carcinomatosis model in mice.
Feifan XieKaat De ClercqChris VervaetJan Van BocxlaerPieter ColinAn VermeulenPublished in: Pharmaceutical research (2019)
The model predicts that the dose range of 7.5-15 mg/kg of PTXnano-GP-MS provides an optimal balance between efficacy and safety.