Elevated retinal cGMP is not associated with elevated circulating cGMP levels in a canine model of retinitis pigmentosa.
Laurence M OccelliKelian SunPaige A WinklerBrandy J MorganSimon M Petersen-JonesPublished in: PloS one (2022)
cGMP levels in the plasma from PDE6A-/- was not elevated when compared to control dogs. At the 2-month timepoint, cGMP plasma levels would not be a useful biomarker for disease.