Ex Vivo Modeling of the PC (Protein C) Pathway Using Endothelial Cells and Plasma: A Personalized Approach.

Nadine SchwarzJens MüllerHamideh YadegariHannah L McRaeSara RedaNasim Shahidi HamedaniJohannes OldenburgBernd PötzschHeiko Rühl

Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)

Patient-specific ex vivo modeling of the PC pathway was achieved using blood-derived ECFCs. The correlation between in and ex vivo APC response rates confirms that the autologous PC model accurately depicts the in vivo situation.

Keyphrases

endothelial cells
bone marrow
cell therapy
stem cells
amino acid