Postsynthetic Modification of Hydrogen-Bonded Frameworks.

Hydrogen-bonded frameworks have garnered significant attention due to their flexible structures with tailored porosity, making them a promising class of porous framework materials. However, the direct synthesis of hydrogen-bonded frameworks with specific functions is highly challenging due to the unpredictable formation of hydrogen-bonded frameworks. In response, postsynthetic modification has emerged as a potent strategy to imbue desired functions into hydrogen-bonded frameworks. Recent advances have demonstrated the effectiveness of postsynthetic modification in hydrogen-bonded frameworks for studying their mechanical, luminescent, electrochemical, and chiral properties. In this concept, we comprehensively summarize the methodologies and outcomes of postsynthetic modification to hydrogen-bonded frameworks, providing a highlight of this exciting research area.