Sleep apnea is associated with the increase of certain genera of Ruminococcaceae and Lachnospiraceae in the gut microbiome of hypertensive patients.

Cheng ZhangFengwei ChenYane ShenYuqing ChenJing Ma

Published in: Expert review of respiratory medicine (2022)

The present study suggests a possible compensatory mechanism for gut microbiome changes in sleep apnea pathophysiology. The positive correlation between HBI and alpha diversity, and increase in certain genera of Ruminococcaceae and Lachnospiraceae in OSA patients may represent an adaptive response to hypoxia.

Keyphrases

sleep apnea
positive airway pressure
obstructive sleep apnea
hypertensive patients
blood pressure
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
patient reported outcomes