Response evaluation after neoadjuvant therapy: evaluation of chemotherapy response score and serological and/or radiological assessment of response in ovarian cancer patients.

Jan Philipp RamspottThaïs BaertMichelle Louise MacKintoshAlexander TrautBeyhan AtasevenMareike BommertFlorian HeitzHelmut PlettStephanie SchneiderKai-Uwe WalteringSebastian HeikausPhilipp HarterAndreas du Bois

Published in: Archives of gynecology and obstetrics (2021)

In this study, evaluation of response to chemotherapy by CRS was not superior to conventional methods (CA125 or radiology). Independent of the evaluation method, response to NACT was predictive of PFS and OS. We observed no added value for CRS as a prognostic marker. The clinical relevance of CRS should be discussed, as no therapeutic consequences result from CRS evaluation.

Keyphrases

locally advanced
end stage renal disease
chronic kidney disease
newly diagnosed
rectal cancer
squamous cell carcinoma
lymph node
patient reported outcomes
deep learning