Glucagon-Like Receptor-1 Agonists and Stroke: a Systematic Review and Meta-Analysis of Cardiovascular Outcome Trials.

Anastasia Adamou Haralampos Milionis Haralampos J Milionis George Ntaios

Published in: International journal of stroke : official journal of the International Stroke Society (2024)

In this meta-analysis of 11 CVOTs with 82,140 participants, GLP-1 RAs demonstrated a 16% relative reduction in stroke risk compared to placebo. This finding may increase implementation of GLP-1 RAs by stroke specialists in individuals with stroke and comorbid diabetes mellitus or obesity.

Keyphrases

atrial fibrillation
healthcare
type diabetes
primary care
metabolic syndrome
insulin resistance
weight loss
cerebral ischemia
physical activity
blood brain barrier
study protocol
double blind
phase iii