An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain.

Yong Fang ZhuKatja Linher-MelvilleMohammad Javad NiazmandManu SharmaAyesha ShahidKan Lun ZhuNatalka ParzeiJesse SidhuChristeene HajRaphael MechoulamGurmit Singh

Published in: British journal of pharmacology (2020)

Initiating treatment of a peripheral nerve injury with CBDA-ME at an early stage post-surgery provides anti-nociception in males, warranting further investigation into potential sexual dimorphisms underlying this response.

Keyphrases

neuropathic pain
peripheral nerve
early stage
spinal cord
spinal cord injury
minimally invasive
coronary artery bypass
mental health
squamous cell carcinoma
bone marrow
cell therapy
sentinel lymph node
neoadjuvant chemotherapy
replacement therapy
percutaneous coronary intervention