Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer.

Adam A KrayaKara N MaxwellBradley WubbenhorstBrandon M WenzJohn PlutaAndrew J RechLiza M DorfmanNicole LuncefordAmanda BarrettNandita MitraJennifer J D MorrissetteMichael FeldmanAnupma NayakSusan M DomchekRobert H VonderheideKatherine L Nathanson

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

HRD scores and hormone receptor subtype are predictive of immunogenicity in BRCA1/2 breast cancers and may inform the design of optimal immune therapeutic strategies.

Keyphrases

breast cancer risk
copy number
genome wide
dna methylation
childhood cancer