Role of [68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of peritoneal carcinomatosis and comparison with [18F]-FDG PET/CT.
Liang ZhaoYizhen PangZuoming LuoKaili FuTingting YangLong ZhaoLong SunHua WuQin LinHaojun ChenPublished in: European journal of nuclear medicine and molecular imaging (2021)
[68Ga]Ga-DOTA-FAPI-04 PET/CT demonstrated superior sensitivity over [18F]-FDG PET/CT for the detection of peritoneal carcinomatosis in patients with various types of cancer, particularly gastric cancer. Furthermore, the uptake of [68Ga]Ga-DOTA-FAPI-04 in peritoneal carcinomatosis was significantly higher than that of [18F]-FDG, demonstrating a larger extent of the lesions and yielding a higher PCI score. This could help enhance the image contrast, improve physicians' diagnostic confidence, and reduce the proportion of missed diagnoses.
Keyphrases
- pet ct
- positron emission tomography
- primary care
- magnetic resonance
- heart failure
- coronary artery disease
- deep learning
- papillary thyroid
- squamous cell carcinoma
- percutaneous coronary intervention
- acute coronary syndrome
- antiplatelet therapy
- st segment elevation myocardial infarction
- coronary artery bypass grafting
- lymph node metastasis