Antidepressants and Quality of Life in Patients with Major Depressive Disorder - Systematic Review and Meta-analysis of Double-blind, Placebo-controlled RCTs.

Antidepressants' effects on QoL are small in primary MDD, and doubtful in secondary major depression and maintenance trials. The strong correlation of QoL and antidepressive effects indicates that the current practice of measuring QoL may not provide sufficient additional insights into the well-being of patients. This article is protected by copyright. All rights reserved.