Mature results of a prospective study of deintensified chemoradiotherapy for low-risk human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Bhishamjit S CheraRobert J AmdurJoel E TepperXianming TanJared M WeissJuneko E Grilley-OlsonD Neil HayesAdam ZanationTrevor G HackmanSamip PatelNathan SheetsMark C WeisslerWilliam M MendenhallPublished in: Cancer (2018)
For patients with favorable-risk human papillomavirus-associated oropharyngeal squamous cell carcinoma, a substantially decreased intensity of therapy with 60 grays of intensity-modulated radiotherapy and weekly low-dose cisplatin produced better preservation of quality of life compared with standard therapies while maintaining excellent 3-year tumor control and survival. Cancer 2018;124:2347-54. © 2018 American Cancer Society.